ROX Index to Predict Risk of Intubation

Predict risk of intubation at 2, 6 and 12 hours in hypoxemic respiratory failure. Not yet validated for COVID-19

ROX Index to Predict Risk of Intubation

Predict risk of intubation at 2, 6 and 12 hours in hypoxemic respiratory failure. Not yet validated for COVID-19

ROX Index to Predict Risk of Intubation

Predict risk of intubation at 2, 6 and 12 hours in hypoxemic respiratory failure. Not yet validated for COVID-19

ROX Index to Predict Risk of Intubation

Predict risk of intubation at 2, 6 and 12 hours in hypoxemic respiratory failure. Not yet validated for COVID-19

1.SpO₂
2.FiO₂
3.Respiratory Rate
Created by on 29/02/2020

By using this site you acknowledge that you have read, understand, and agree to be bound by our terms of use and privacy policy. All content and tools are for educational use only, are not meant to be a substitute for professional advice and should not be used for medical diagnosis and/or medical treatment.

About this Calculator

During high-flow nasal cannula (HFNC) therapy in patients with acute hypoxemic respiratory failure, it can be desirable not to delay intubation and have an adverse event.

The ROX index, defined as the ratio of oxygen saturation as measured by pulse oximetry/FIO2 to respiratory rate, has been assessed as a predictor of the need to intubate in patients received HFNC oxygen therapy.

Prediction accuracy of the ROX index increased over time with AUC of 0.679 at 2 h, 0.703 at 6 hours and 0.759 at 12 hours.

ROX &ge:4.88 at 2, 6 and 12 hours after HFNC initiation was associated with a lower risk for intubation.

Predictors of HFNC failure include:

  • ROX <:2.85 at 2 hours
  • ROX <:3.47 at 6 hours
  • ROX <:3.85 at 12 hours

References

Roca O et al.

An Index Combining Respiratory Rate and Oxygenation to Predict Outcome of Nasal High-Flow Therapy.

American Journal of Respiratory and Critical Care Medicine 2019 June 1, 199 (11): 1368-1376.

The ROX Index to Predict Risk of Intubation calculator is created by QxMD.

1. SpO₂

%
More Information

SpO₂ represents peripheral capillary oxygen saturation

Created by on 29/02/2020

By using this site you acknowledge that you have read, understand, and agree to be bound by our terms of use and privacy policy. All content and tools are for educational use only, are not meant to be a substitute for professional advice and should not be used for medical diagnosis and/or medical treatment.

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