Generalized Anxiety Disorder 2 (GAD-2)

Ultra-brief screening for anxiety disorders


The Generalized Anxiety Disorder two questions scale (GAD-2) was developed by Drs. Robert L. Spitzer, Janet B.W. Williams, Kurt Kroenke and colleagues, with an educational grant from Pfizer, Inc. The Generalized Anxiety Disorder scales originated from The Primary Care Evaluation of Mental Disorders (PRIME-MD) which was a questionnaire developed and validated in the early 1990s to efficiently diagnose five of the most common types of mental disorders presenting in medical populations: depressive, anxiety, somatoform, alcohol, and eating disorders.

It’s predecessor the Generalized Anxiety Disorder seven questions scale (GAD-7) has a larger research base, and is more common in clinical use. The GAD-2 is an ultra brief and easy to perform initial screening tool for Generalized Anxiety Disorder (GAD). In primary care patients, the GAD-2 has been shown to has high sensitivity and specificity. Designed as a screening tool for generalized anxiety, the GAD-2 can have false positives for other diagnosis such as Panic Disorder, Social Anxiety Disorder, and Posttraumatic Stress Disorder. It alone isn’t sufficient to diagnose, monitor treatment or grade severity. Any positive screening should always be followed up with a clinical interview.


Kroenke K, Spitzer RL, Williams JB, Monahan PO, Löwe B.

Annals of Internal Medicine 2007 March 6, 146 (5): 317-25

Spitzer RL, Williams JBW, Kroenke K, Linzer M, deGruy FV, Hahn SR, Brody D, Johnson JG.

JAMA 1994 December 14, 272 (22): 1749-56

The Generalized Anxiety Disorder 2 (GAD-2) calculator is created by QxMD.

By using this site you acknowledge that you have read, understand, and agree to be bound by our terms of use and privacy policy. All content and tools are for educational use only, are not meant to be a substitute for professional advice and should not be used for medical diagnosis and/or medical treatment.

1. Over the last 2 weeks, how often have you been bothered by feeling nervous, anxious or on edge?

0/2 completed