Diagnosis of Progressive Supranuclear Palsy (PSP)

Diagnosis of Progressive Supranuclear Palsy (PSP)

About

The 2017 Movement Disorder Society Criteria aim to improve upon previous diagnostic criteria by elucidating the distinct subtypes of the disease. All patients must have sporadic presentation after the age of 40 and subsequently progress. The criteria rest upon four clinical domains: oculomotor dysfunction, postural instability, akinesia, and cognitive dysfunction. Definite PSP can only be diagnosed upon autopsy, but the clinical criteria aim to diagnose 'Probable PSP' with a high degree of specificity. The category of 'Possible PSP' is has high sensitivity, but this comes at the cost of specificity. The least specific category is 'Suggestive of PSP'. The omission of limb dystonia as an aspect of corticobasal syndrome was corrected in a subsequent publication by the authors.

References

Hoglinger GU, Respondek G, Stamelou M et al.

Movement Disorders 2017 Jun; 32(6):853-864.

Grimm MJ, Respondek G, Stamelou M et al.

Movement Disorders 2019 Mar 18; 34 (8): 1228-1232.

The Diagnosis of Progressive Supranuclear Palsy (PSP) calculator is created by QxMD.

By using this site you acknowledge that you have read, understand, and agree to be bound by our terms of use and privacy policy. All content and tools are for educational use only, are not meant to be a substitute for professional advice and should not be used for medical diagnosis and/or medical treatment.

1. Does the patient have a sporadic, progressive disorder with onset at or after the age of 40?

0/15 completed