Primary Progressive Multiple Sclerosis: Diagnosis

Diagnose Primary Progressive MS using the 2017 McDonald Criteria

Primary Progressive Multiple Sclerosis: Diagnosis

Diagnose Primary Progressive MS using the 2017 McDonald Criteria

Primary Progressive Multiple Sclerosis: Diagnosis

Diagnose Primary Progressive MS using the 2017 McDonald Criteria

Primary Progressive Multiple Sclerosis: Diagnosis

Diagnose Primary Progressive MS using the 2017 McDonald Criteria

1.1 year of disability progression (retrospectively or prospectively determined) independent of clinical relapse?
2.One or more T2-hyperintense lesions characteristic of multiple sclerosis in one or more of the following brain regions: periventricular, cortical or juxtacortical, or infratentorial?
3.Two or more T2-hyperintense lesions in the spinal cord?
4.Presence of CSF-specific oligoclonal bands?
Created by on 07/00/2016

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About this Calculator

The 2017 McDonald Criteria for Diagnosis of MS were compiled by the International Panel on Diagnosis of Multiple Sclerosis. Unlike Relapsing-Remitting MS, patients with Primary Progressive MS experience disability progression independent of clinical relapses. The main revisions from the 2010 McDonald Criteria for PPMS are: symptomatic lesions can now be used to fulfill criteria, and cortical lesions are seen as equivalent to juxtacortical lesions. The requirements for spinal cord lesion and for positive unmatched oligoclonal bands in the CSF remain the same.

References

Thompson, A., Banwell, B., Barkhof, F., Carroll, W., Coetzee, T., Comi, G., Correale, J., Fazekas, F., Filippi, M., Freedman, M., Fujihara, K., Galetta, S., Hartung, H., Kappos, L., Lublin, F., Marrie, R., Miller, A., Miller, D., Montalban, X., Mowry, E., Sorensen, P., Tintoré, M., Traboulsee, A., Trojano, M., Uitdehaag, B., Vukusic, S., Waubant, E., Weinshenker, B., Reingold, S. and Cohen, J.

Diagnosis of multiple sclerosis: 2017 revisions of the McDonald criteria.

Lancet Neurology 2018, 17 (2): 162-173

The Primary Progressive Multiple Sclerosis: Diagnosis calculator is created by QxMD.

1. 1 year of disability progression (retrospectively or prospectively determined) independent of clinical relapse?

Created by on 07/00/2016

By using this site you acknowledge that you have read, understand, and agree to be bound by our terms of use and privacy policy. All content and tools are for educational use only, are not meant to be a substitute for professional advice and should not be used for medical diagnosis and/or medical treatment.

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