Predict risk of rupture for asymptomatic intracranial aneurysms


The PHASES score is an aid for prediction of the risk of rupture for asymptomatic intracranial aneurysms.

The score is based on a systematical review of six prospective cohort studies with subarachnoid hemorrhage as outcome. 8382 participants in the USA, Europe and Japan were included.

Several factors were independently associated with risk of rupture, including genetic background, age, hypertension, earlier SAH from another aneurysm, size and location of the aneurysm. A Cox proportional hazards model was generated based on these risk factors, resulting in an estimate of the absolute 5-years risk of rupture of an aneurysm.


Greving JP, Wermer MJH, Brown RD Jr, Morita A, Juvela S, Yonekura M, Ishibashi T, Torner JC, Nakayama T, Rinkel GJE, Algra A.

Lancet Neurology 2014, 13 (1): 59-66

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