Dialysis Duration Needed for Ethylene Glycol Ingestion

Estimate dialysis duration required for ethylene glycol poisoning


1.Total Body Water?
2.Initial Ethylene Glycol Concentration?
3.Dialyzer Urea Clearance?


In a toxic alcohol ingestion with ethylene glycol or methanol, dialysis is often required.

The duration of hemodialysis in hours required to achieve a toxin concentration of ≤5 mmol/L can be estimated using the formula [-V ln(5/A)]/0.06k, where V is total body water in liters, A is the initial alcohol concentration in mmol/L, and k is 80 percent of the dialyzer urea clearance in mL/min at the observed blood flow rate.


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A simple method to estimate the required dialysis time for cases of alcohol poisoning.

Kidney International 2001, 60 (5): 2021-4

McMurray M, Carty D, Toffelmire EB.

Predicting methanol clearance during hemodialysis when direct measurement is not available.

CANNT Journal 2002, 12 (1): 29-38; quiz 32-3

Burns AB, Bailie GR, Eisele G, McGoldrick D, Swift T, Rosano TG.

Use of pharmacokinetics to determine the duration of dialysis in management of methanol poisoning.

American Journal of Emergency Medicine 1998, 16 (5): 538-40

Created by on 13/08/2017

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1. Total Body Water?

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