Dialysis Duration Needed for Methanol Ingestion
Estimate dialysis duration required for methanol poisoning
In a toxic alcohol ingestion with ethylene glycol or methanol, dialysis is often required.
The duration of hemodialysis in hours required to achieve a toxin concentration of ≤5 mmol/L can be estimated using the formula [-V ln(5/A)]/0.06k, where V is total body water in liters, A is the initial alcohol concentration in mmol/L, and k is 80 percent of the dialyzer urea clearance in mL/min at the observed blood flow rate.
Hirsch DJ, Jindal KK, Wong P, Fraser AD.
Youssef GM, Hirsch DJ.
McMurray M, Carty D, Toffelmire EB.
Burns AB, Bailie GR, Eisele G, McGoldrick D, Swift T, Rosano TG.
1. Total Body Water?
Watson estimate of total-body water in liters