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The Crohn's Disease Activity Index (CDAI) is utilized in clinical trials to assess disease activity in Crohn's.
CDAI scores can range from 0 to ~600.
A cut-off value of <150 was selected so that most patients below this threshold would be rated by physicians as 'very well'.
The delineator between active and very severe disease was defined as a cut-off value of 450 points.
CDAI scores of 150–219 has been labelled as mildly active disease and scores of 220–450 as moderately active disease.
CDAI has some limitations, which include:
References
Best WR.
Predicting the Crohn's disease activity index from the Harvey-Bradshaw Index.
Inflamm Bowel Dis. 2006 Apr;12(4):304-10.
Best WR, Becktel JM, Singleton JW, Kern F Jr.
Development of a Crohn's disease activity index. National Cooperative Crohn's Disease Study.
Gastroenterology. 1976 Mar;70(3):439-44.
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