ASDAS-ESR (Ankylosing Spondylitis Disease Activity Score)

Assess disease activity in Ankylosing Spondylitis.

ASDAS-ESR (Ankylosing Spondylitis Disease Activity Score)

Assess disease activity in Ankylosing Spondylitis.

ASDAS-ESR (Ankylosing Spondylitis Disease Activity Score)

Assess disease activity in Ankylosing Spondylitis.

ASDAS-ESR (Ankylosing Spondylitis Disease Activity Score)

Assess disease activity in Ankylosing Spondylitis.

1.Back Pain Severity? (Rate From 0-10)
2.Duration of Morning Stiffness? (Rate From 0-10)
3.Patient Global Assessment of Disease Activity? (Rate From 0-10)
4.Peripheral Pain/Swelling? (Rate From 0-10)
5.ESR?
Created by on 28/10/2015

By using this site you acknowledge that you have read, understand, and agree to be bound by our terms of use and privacy policy. All content and tools are for educational use only, are not meant to be a substitute for professional advice and should not be used for medical diagnosis and/or medical treatment.

About this Calculator

The Ankylosing Spondylitis Disease Activity Score (ASDAS) is an index to assess disease activity in Ankylosing Spondylitis (AS).

The prefered score uses CRP, rather than ESR.

ASDAS-CRP = 0.12 x Back Pain + 0.06 x Duration of Morning Stiffness + 0.11 x Patient Global + 0.07 x Peripheral Pain/Swelling + 0.58 x Ln(CRP+1)

ASDAS-ESR = 0.08 x Back Pain + 0.07 x Duration of Morning Stiffness + 0.11 x Patient Global + 0.09 x Peripheral Pain/Swelling + 0.29 x √(ESR)

Back pain, patient global assessment, duration of morning stiffness and peripheral pain/swelling are all assessed on a numerical rating scale (from 0 to 10).

The 3 cut-offs selected to separate these states (figure 1) were: <1.3 between "inactive disease" and "moderate disease activity", <2.1 between "moderate disease activity" and "high disease activity", and >3.5 between "high disease activity" and "very high disease activity".

Cut-offs for improvement scores were: a change ≥1.1 units for "clinically important improvement" and a change ≥2.0 units for "major improvement".

References

Lukas C, Landewé R, Sieper J, Dougados M, Davis J, Braun J, van der Linden S, van der Heijde D.

Development of an ASAS-endorsed disease activity score (ASDAS) in patients with ankylosing spondylitis.

Annals of the Rheumatic Diseases 2009, 68 (1): 18-24

van der Heijde D, Lie E, Kvien TK, Sieper J, van den Bosch F, Listing J, Braun J, Landewé R.

ASDAS, a highly discriminatory ASAS-endorsed disease activity score in patients with ankylosing spondylitis.

Annals of the Rheumatic Diseases 2009, 68 (12): 1811-8

Machado P, Landewé R, Lie E, Kvien TK, Braun J, Baker D, van der Heijde D.

Ankylosing Spondylitis Disease Activity Score (ASDAS): defining cut-off values for disease activity states and improvement scores.

Annals of the Rheumatic Diseases 2011, 70 (1): 47-53

1. Back Pain Severity? (Rate From 0-10)

More Information

Ask "How would you describe the overall level of AS neck, back or hip pain you have had?"

Created by on 28/10/2015

By using this site you acknowledge that you have read, understand, and agree to be bound by our terms of use and privacy policy. All content and tools are for educational use only, are not meant to be a substitute for professional advice and should not be used for medical diagnosis and/or medical treatment.

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