BODE Index for COPD

Estimate prognosis in COPD


This formula is taken from Celli et al (2004), based on the evaluation of 207 patients with COPD and the subsequent prospective validation on a similar cohort of 625 patients. Patients were recruited in the United States, Venezuela, and Spain and all were judged to have stable COPD.

61% of deaths were secondary to respiratory insufficiency. Multiple variables were assessed and each was evaluated as a possible independent predictor of mortality. FEV1, body-mass index, 6-minute walk distance, and the modified MRC dyspnea scale were found to be the best predictors of death among these variables. The BODE Index predicts all-cause mortality and respiratory-related mortality with better accuracy than the FEV1 alone.

The hazard ratio for all-cause mortality is 1.34 for every one-point increase in the BODE score. The hazard ratio for respiratory-related mortality is 1.62 for every one-point increase in the BODE score.


Celli BR et al.

Respir Med 2008;102(Suppl 1):S27

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1. FEV₁ (% predicted)?

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