Schwartz Pediatric eGFR, Full Model (2009)
The full Schwartz pediatric eGFR calculation requires height, serum creatinine, cystatin C, blood urea nitrogen and gender.
The original Schwartz eGFR formula was devised in the mid-1970s to estimate GFR in children. This model was felt to overestimates GFR, likely a result of a change in methods used to measure creatinine.
In 2009, Schwartz et al developed a revised estimated GFR formula using data from cohort of children in the Chronic Kidney Disease in Children (CKiD) study.
This model is appropriate for children between the ages of 1 to 16 yr.
The linear regression analyses generated a model that included the following:
- height (meters)
- serum creatinine (mg/dL)
- cystatin C (mg/L)
- Blood urea nitrogen (mg/dL)
The full equation is as follows:
- GFR (ml/min per 1.73 m2) =
- 39.1[height/creatinine]0.516 X [1.8/cystatin C]0.294 [30/BUN]0.169 [1.099]male [height/1.4]0.188
Given the complexity of this formula, a "bedside" version requiring only height and creatinine was developed:
eGFR = 0.413 X (height/serum creatinine),
where height is in cm, and creatinine is in mg/dL
Schwartz GJ, Muñoz A, Schneider MF, Mak RH, Kaskel F, Warady BA, Furth SL.
Journal of the American Society of Nephrology: JASN 2009, 20 (3): 629-37
The Schwartz Pediatric eGFR, Full Model (2009) calculator is created by QxMD.