Bleeding Risk in Atrial Fibrillation: OBRI

The Outpatient Bleeding Risk Index (OBRI) estimates risk of bleeding in AF while on oral anticoagulation.


The use of oral anticoagulation is associated with an increased risk of minor (non-life threatening) and major (potentially life threatening) bleeding. Knowledge of the risk of major bleeding with warfarin therapy, as estimated by the Outpatient Bleeding Risk Index (OBRI), could help guide anticoagulation therapy. For example, if a patient with atrial fibrillation has a high risk of major bleeding and a low risk of stroke then anticoagulation may be harmful.


Aspinall SL, DeSanzo BE, Trilli LE, et al.

Journal of General Internal Medicine 2005, 20 (11): 1008-13

The Bleeding Risk in Atrial Fibrillation: OBRI calculator is created by QxMD.

By using this site you acknowledge that you have read, understand, and agree to be bound by our terms of use and privacy policy. All content and tools are for educational use only, are not meant to be a substitute for professional advice and should not be used for medical diagnosis and/or medical treatment.

1. Age?

0/4 completed