Phenytoin Adjustment in Renal Failure

Phenytoin Adjustment in Renal Failure

Phenytoin Adjustment in Renal Failure

Phenytoin Adjustment in Renal Failure

1.Measured Total Phenytoin Concentration?
2.Albumin?
3.eGFR?
Created by on 13/11/2015

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About this Calculator

Phenytoin has significant albumin binding and when total phenytoin level is measured, it is assumed that the amount bound to albumin versus free is predictable. In advanced renal failure, there is reduced phenytoin binding to albumin and one will tend to underestimate free phenytoin levels. The correction factor provided in this tool will provide a better sense of the adjusted phenytoin level, though a measure of free phenytoin is more reliable.

References

The Phenytoin Adjustment in Renal Failure calculator is created by QxMD.

1. Measured Total Phenytoin Concentration?

Created by on 13/11/2015

By using this site you acknowledge that you have read, understand, and agree to be bound by our terms of use and privacy policy. All content and tools are for educational use only, are not meant to be a substitute for professional advice and should not be used for medical diagnosis and/or medical treatment.

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