Prognosis in Renal Cell Carcinoma (UISS)

Estimate survival in renal cell carcinoma


1.Tumor Size (in greatest dimension)?
2.Tumor directly invades the adrenal gland or perinephric tissues but not beyond Gerota's fascia?
3.Tumor grossly extends into the renal vein or its segmental (muscle-containing) branches, or vena cava below the diaphragm?
4.Tumor grossly extends into the vena cava above the diaphragm or invades the wall of the vena cava?
5.Tumor invades beyond Gerota's fascia?
6.Regional Lymph Nodes?
7.Distant Metastasis?
8.Fuhrman's Grade?
9.ECOG Status?


The UCLA integrated staging system (UISS) is a validated prognostic model that includes the Eastern Cooperative Oncology Group performance status, Fuhrman's histologic grade and the TNM anatomic staging system. Using these variables, five prognostic categories were identified that correlate with post-nephrectomy outcome.


Zisman, A, Pantuck, A, Dorey, F, et al.

Improved prognostication of renal cell carcinoma using an integrated staging system.

Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology 2001 March 15, 19 (6): 1649-57

The Prognosis in Renal Cell Carcinoma (UISS) calculator is created by QxMD.

Created by on 08/01/2016

By using this site you acknowledge that you have read, understand, and agree to be bound by our terms of use and privacy policy. All content and tools are for educational use only, are not meant to be a substitute for professional advice and should not be used for medical diagnosis and/or medical treatment.

1. Tumor Size (in greatest dimension)?

0/9 completed