Kt/V from PRU

Quantify hemodialysis adequacy


Result 1 is calculated using the following formula:
Kt/V = (0.026 - PRU) - 0.460

Result 2 is calculated using the following formula:
Kt/V = (0.24 - PRU) - 0.276

Recall that:
Percent Reduction Urea (PRU) = (1  -  [postdialysis BUN  ÷  predialysis BUN]) X 100%

These equations are frequently used because of their simplicity, and though reasonably accurate, are generally felt to be inferior to the forumula used in our calculator entitled "Kt/V Daugirdas". Although using the PRU is useful as an epidemiologic tool, its utility in individual patients is more limited because of the considerable range of Kt/V that can be seen for any given PRU. Part of this variability is due to the fact that PRU does not take into account urea removal that occurs with ultrafiltration.


Daugirdas JT.

ASAIO Transactions 1990, 36 (3): M362-4

Lowrie EG, Lew NL.

The urea reduction ratio (URR). A simple method for evaluating hemodialysis treatment. Contemp Dial Nephrol 1992; 12:11.

The Kt/V from PRU calculator is created by QxMD.

By using this site you acknowledge that you have read, understand, and agree to be bound by our terms of use and privacy policy. All content and tools are for educational use only, are not meant to be a substitute for professional advice and should not be used for medical diagnosis and/or medical treatment.

1. Percent Reduction of Urea?

0/1 completed