Kt/V from PRU
Quantify hemodialysis adequacy
Result 1 is calculated using the following formula:
Kt/V = (0.026 - PRU) - 0.460
Result 2 is calculated using the following formula:
Kt/V = (0.24 - PRU) - 0.276
Percent Reduction Urea (PRU) = (1 - [postdialysis BUN ÷ predialysis BUN]) X 100%
These equations are frequently used because of their simplicity, and though reasonably accurate, are generally felt to be inferior to the forumula used in our calculator entitled "Kt/V Daugirdas". Although using the PRU is useful as an epidemiologic tool, its utility in individual patients is more limited because of the considerable range of Kt/V that can be seen for any given PRU. Part of this variability is due to the fact that PRU does not take into account urea removal that occurs with ultrafiltration.
Lowrie EG, Lew NL.