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Prognosis depends on the sum of 5 factors (the mnemonic NoLASH may be useful):
Number of Nodal areas
The Follicular Lymphoma International Prognostic Index (FLIPI) is the result of a large international cooperative effort in which clinical data was collected from 4167 patients with FL diagnosed between 1985 and 1992. From this database, a prognostic index with five adverse factors was derived and validated. The index is able to separate 3 risk groups of approximately eqaul size with clear differentiation of long-term prognosis.
The FLIPI was proposed and validated by revised/developed by Solal-Celigny et al. Follicular Lymphoma International Prognostic Index. Blood 2004;104:1258-1265.
View Abstract Full Text from Blood