Universal Definition of MI
Spontaneous MI related to ischaemia due to a primary coronary event such as plaque erosion and/or rupture, fissuring, or dissection.
MI secondary to ischaemia due to either increased oxygen demand or decreased supply, e.g. coronary artery spasm, coronary embolism, anaemia, arrhythmias, hypertension, or hypotension.
Sudden unexpected cardiac death, including cardiac arrest, often with symptoms suggestive of myocardial ischaemia, accompanied by presumably new ST elevation, or new LBBB, or evidence of fresh thrombus in a coronary artery by angiography and/or at autopsy, but death occurring before blood samples could be obtained, or at a time before the appearance of cardiac biomarkers in the blood.
MI associated with PCI. Increases of biomarkers above the 99th percentile URL indicate of peri-procedural myocardial necrosis (normal baseline troponin). Increases of biomarkers greater than 3 x 99th percentile URL define defining PCI-related MI.
MI associated with stent thrombosis as documented by angiography or at autopsy.
MI associated with CABG. Increases of biomarkers above the 99th percentile URL indicate of peri-procedural myocardial necrosis (normal baseline troponin). Increases of biomarkers greater than 5 x 99th percentile URL plus either new pathological Q waves or new LBBB, or angiographically documented new graft or native coronary artery occlusion, or imaging evidence of new loss of viable myocardium have been designated as defining CABG-related myocardial infarction.