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A fractional excretion of urea (FEUrea) of < 35% is suggestive of pre-renal azotemia. Unlike when measuring of the fractional excretion of sodium, (FENa), it can be used even when patients are taking diuretics.
Fractional Exceretion of Urea = Uur X Pcreat / Ucreat X Pur · 100%
Uur = Urine urea
Pcreat = Plasma creatinine
Ucreat = Urine creatinine
Pur = Plasma urea
Adapted from Carvounis et al. Significance of the fractional excretion of urea in the differential diagnosis of acute renal failure. Kidney Int 2002; 62: 2223–2229.