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The model used to calculate the risk of contrast nephropathy post-percutaneous intervention is taken from:
Mehran et al. A Simple Risk Score for Prediction of Contrast-Induced Nephropathy After Percutaneous Coronary Intervention J Am Coll Cardiol 2004;44:1393-9.
In this study, patients were given IV half-normal saline at a rate of 1 mL/kg/h for 4 to 12 h before PCI and 18 to 24 h after PCI.
Contrast-induced nephropathy - increase of >25% or >0.5 mg/dl / >44 micromol/L in pre-PCI serum creatinine at 48 h after PCI.
Anemia - baseline hematocrit value <39% for men and <36% for women.
Hypotension - systolic blood pressure <80 mm Hg for at least 1 h requiring inotropic support with medications or intra-aortic balloon pump (IABP) within 24 h periprocedurally.
Congestive Heart Failure - NYHA III or IV or prior pulmonary edema