A resource of Calculate by QxMD at https://www.qxmd.com/calculate
Over 400 decision support tools available • get the app for iOS or Android at qx.md/calculate
The recommendation to avoid high-osmolar contrast media is based on older literature, since recent RCTs comparing high- vs. low- and iso-osmolar iodine-based contrast media are not available. In addition, high-osmolar contrast media have virtually been abandoned in modern radiological units. Both the review of Goldfarb et al.,448 and the meta-analysis of Barrett and Carlisle combining 24 randomized studies449 suggest that the risk of CI-AKI is similarly low with highosmolar and low-osmolar agents among otherwise stable patients with normal renal function, but that in contrast to high-osmolar contrast media, low-osmolar contrast media are less nephrotoxic in patients with pre-existing kidney function impairment.
Do you have an enquiry or suggestion? Get in touch with us through Twitter @QxMD, Facebook QxMD, or email contact@qxmd.com