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CKD, AKD, and AKI are defined by parameters expressing the level of kidney function. Table 12 gives examples of each condition based on GFR and different magnitudes of increase in SCr.
To illustrate the relationship of changes in SCr to changes in eGFR, we simulated changes in eGFR that would result from changes in SCr corresponding to the KDIGO definition of AKI in the Chronic Kidney Disease Epidemiology Collaboration cohort.67,68 Figure 6 shows the relationship of these changes in eGFR to the definition and stages of AKI. Not all patients with AKI would meet the eGFR criteria for the definition of AKD.
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