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The IPSSWM was derived after merging a cohort of patients with WM from 7 international co-operative groups. The IPSSWM speicifcially focuse on symptomatic patinets requiring therapy, and the majority were treated with standard therapies including alkylating agents, purine analogs, and rituximab.
Citations
Morel P1, Duhamel A, Gobbi P, Dimopoulos MA, Dhodapkar MV, McCoy J, Crowley J, Ocio EM, Garcia-Sanz R, Treon SP, Leblond V, Kyle RA, Barlogie B, Merlini G.
International prognostic scoring system for Waldenstrom macroglobulinemia.
Blood. 2009 Apr 30;113(18):4163-70. doi: 10.1182/blood-2008-08-174961. Epub 2009 Feb 5.
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