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The McMahon score was developed to predict the risk of severe acute kidney injury or mortality in patients presenting to the hospital with rhabdomyolysis (defined as a serum CPK on admission of >1000 U/L and a peak CPK of >5000 U/L)
The score identifies a low risk population who are unlikely to have severe adverse outcomes including AKI as a result of the injury. The AUC for the final model was 0.82 in the entire cohort.
The score was validated in a follow-up paper by an independent group.
References
McMahon GM, Zeng X, Waikar SS
A risk prediction score for kidney failure or mortality in rhabdomyolysis
JAMA Intern Med 2013 Oct 28;173(19):1821-8
Simpson JP1, Taylor A, Sudhan N, Menon DK, Lavinio A.
Rhabdomyolysis and acute kidney injury: creatine kinase as a prognostic marker and validation of the McMahon Score in a 10-year cohort: A retrospective observational evaluation.
Eur J Anaesthesiol. 2016 Dec;33(12):906-912.
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