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NSAIDs can put patients at risk of acute kidney injury. This calculator to estimate patients' risk of acute kidney injury or hyperkalemia within 30 days following initiation of a prescription NSAID was developed in a large retrospective population-based study of adults 66 years and older using linked administrative and laboratory databases in Ontario, Canada.
Acute kidney injury was defined as a serum creatinine increase of 50% or more, or an absolute increase of at least 0.3 mg/dL (26.5 umol/L).
Hyperkalemia was defined as serum potassium concentration of 5.5 mmol/L or greater.
References
Nonsteroidal anti-inflammatory drug use and risk of acute kidney injury and hyperkalemia in older adults: a population-based study. Nash DM, et al. Nephrology, Dialysis, Transplantation 2019.
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