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For use in blunt trauma patients. Validated in a large multi-centered trial that included over 34,000 patients. Sensitivity was reported at 99.6% with a specificity of 12.9%. The rule was validated in all age ranges over 1 year, however the small numbers in the study suggest caution may be required in children under 18 years.
A comparison study between the NEXUS Criteria and the Canadian C-Spine Rule suggested that the NEXUS criteria are less sensitive (90.7 vs. 95-99%), though there remains some controversy over the results and methodology.
References
Hoffman et al. Validity of a set of clinical criteria to rule out injury to cervical spine in patients with blunt trauma. NEJM 343, p.94, 2000.
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Viccellio et al. A prospective multicenter study of cervical spine injury in children. Pediatrics. 108, p.E20, 2001.
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Stiell et al. The Canadian C-Spine Rule versus the NEXUS Low-Risk Criteria in Patients with Trauma. NEJM Vol 349, p.2510, 2003
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