APRI (AST to Platelet Ratio Index)

Assess likelihood of fibrosis or cirrhosis non-invasively using AST and platelet count.

About

The AST to Platelet Ratio Index (APRI) tool has been found to useful as a non-invasive index that correlates with liver biopsy findings of fibrosis and cirrhosis.

In a meta-analysis by Lin et al, it was found that in patients with hepatitis C, an APRI score greater than 1.0 had a sensitivity of 76% and specificity of 72% for predicting cirrhosis. In addition, it was found that an APRI score greater than 0.7 had a sensitivity of 77% and specificity of 72% for predicting significant hepatic fibrosis.

References

Lin ZH, Xin YN, Dong QJ, et al.

Performance of the aspartate aminotransferase-to-platelet ratio index for the staging of hepatitis C-related fibrosis: an updated meta-analysis.

Hepatology: Official Journal of the American Association for the Study of Liver Diseases 2011, 53 (3): 726-36

The APRI (AST to Platelet Ratio Index) calculator is created by QxMD.

Created by on 05/01/2016

By using this site you acknowledge that you have read, understand, and agree to be bound by our terms of use and privacy policy. All content and tools are for educational use only, are not meant to be a substitute for professional advice and should not be used for medical diagnosis and/or medical treatment.

1. AST?

U/L
0/3 completed