APRI (AST to Platelet Ratio Index)
Assess likelihood of fibrosis or cirrhosis non-invasively using AST and platelet count.
The AST to Platelet Ratio Index (APRI) tool has been found to useful as a non-invasive index that correlates with liver biopsy findings of fibrosis and cirrhosis.
In a meta-analysis by Lin et al, it was found that in patients with hepatitis C, an APRI score greater than 1.0 had a sensitivity of 76% and specificity of 72% for predicting cirrhosis. In addition, it was found that an APRI score greater than 0.7 had a sensitivity of 77% and specificity of 72% for predicting significant hepatic fibrosis.
Lin ZH, Xin YN, Dong QJ, et al.