| DRUG |
Cefazolin |
| IP DOSE |
20 mg/kg IP every day, in long dwell |
| DRUG |
Cefepime |
| IP DOSE |
1 g IP in one exchange per day |
| DRUG |
Fluconazole |
| IP DOSE |
200 mg IP in one exchange per day every 24–48 hours |
| DRUG |
Tobramycin |
| IP DOSE |
Loading dose 1.5 mg/kg IP in the long dwell
Maintenance dose 0.5 mg/kg in one exchange per day in the long dwell |
| DRUG |
Vancomycin* |
| IP DOSE |
Loading dose 30 mg/kg IP in long dwell, repeat dosing 15 mg/kg IP in long dwell every 3–5 days, following levels (keep trough levels > 15 µg/mL) |
IP= intraperitoneal
- * Supplemental doses may be needed for APD pts6
- * On day 5, approximately 25% of CAPD patients will not achieve a peritoneal dialysis effluent (PDE) vancomycin concentration greater than 4 mg/L during daytime exchanges. For APD patients in whom dwell times are even shorter (often less than 2 hours), it is likely that an even higher proportion will have “low” PDE vancomycin concentrations for the duration of nighttime treatment.11
Adapted from Table 5. Courtesy of Multimed Inc.
