Fungal Peritonitis*
Yeast or other fungus on Gram stain/microscopy3 or culture1
Remove catheter immediately1
Initial therapy may be a combination of amphotericin B† and flucytosine.1**
Other agents are echinocandins, fluconazole, voriconazole, posaconazole1
Treat for at least 14 days of anti-fungal agent after catheter removal1
IP amphotericin causes chemical peritonitis and pain, while IV administration has poor peritoneal bioavailability.1
*Fungal peritonitis is often preceded by courses of antibiotics.1
**If flucytosine is used, monitor serum concentration levels to avoid bone marrow toxicity (peak serum levels 1–2 hours after dose should be 25–50 mcg/mL)1
