IP=intra-peritoneal
* Continued assessment and modification of therapy based on culture and sensitivity results; refer to subsequent sections for specific organisms cultured.3 Exchange that contains antibiotics must be a minimum 6-hour dwell.1
† Vancomycin may be considered if patient has a history of methicillin-resistant Staphylococcus aureus colonization/infection, is seriously unwell, or has a history of severe allergy to penicillins and cephalosporins. If the center has an increased rate of methicillin resistance, vancomycin may also be considered.3
‡ If the patient is cephalosporin allergic, aztreonam is an alternative to ceftazidime or cefepime. Vancomycin and ceftazidime are compatible when mixed in a dialysis solution volume greater than 1 L; however, they are incompatible when mixed in the same syringe or empty dialysis solution bag for reinfusion. Aminoglycosides should not be added to the same exchange with penicillins as this results in incompatibility.1